While the Coliseum served as home field for both USC and UCLA at the time, the iconic crosstown rivalry met for the first time on September 28, 1929. The game was the season opener for both teams. USC was coming off its first national championship season while UCLA had just completed its first season in the Pacific Coast Conference. The Trojans were led by legendary coach Howard Jones and defeated the Bruins 76-0, which still stands as the most lopsided score of the series.
As of the 2022 season, USC leads the all-time series with 50 wins while UCLA has 33 wins. There have been seven ties in the series.